Theophylact of Ohrid

And he arose and took the young Child and His mother by night, and departed into Egypt; and was there until the death of Herod: that it might be fulfilled which was spoken by the Lord through the prophet, saying, "Out of Egypt have I called My Son" (Hosea 11:1). The Jews say that this was said of the people whom Moses led out of Egypt. We reply, is it anything remarkable that something which was spoken of the people in type as a foreshadowing, was realized by Christ in truth? Furthermore, who is the Son of God? …

Commentary on Matthew ↗

Hilary of Poitiers

Egypt full of idols; for after this enquiry for Him among the Jews, Christ leaving Judæa goes to be cherished among nations given to the vainest superstitions.

Catena Aurea by Aquinas ↗

Thomas Aquinas

And he rose. Here is mentioned the execution of the angel's command both as to the flight and the length of the stay. He rose and took the child and his mother. The time is mentioned, when he says at night, on account of the fear and distress: "My soul desired you at night," i.e., in distress (Is 26:9); for in times of distress one must have recourse to God: "In the morning, they will come to me in their trouble" (Hos 10:1). He rose. …

Commentary on Matthew ↗