Ambrose of Milan

If the union of Adam and Eve is a great mystery in Christ and in the church, it is certain that as Eve was bone of the bones of her husband and flesh of his flesh, we also are members of Christ's body, bones of his bones and flesh of his flesh.

Letters ↗

Bede

Wherefore a man shall leave his father and mother, and shall cleave to his wife, and they shall be two in one flesh. Though the Scripture itself testifies that these words were first said by man, yet the Lord in the Gospel declared that God said them. For He said: Have you not read that He who made them from the beginning made them male and female, and said: For this cause shall a man leave his father and mother and shall cleave to his wife, and they shall be two in one flesh (Matt. …

Commentary on Genesis (Hexaemeron) ↗

Bonaventure

And the Lord said: "For this reason a man shall leave his father and mother and shall cleave to his wife." And the Apostle said: "This is a great sacrament; but I speak in Christ and in the Church." Was not the Church formed from the side of Christ, when Christ fell asleep on the cross? And from His side flowed forth blood and water, that is, the Sacraments, through which the Church is reborn. From the rib of Adam, Eve was formed, who was joined to him in marriage. …

Collationes de Septem Donis, Collation 6 ↗