Theophylact of Ohrid

The goodness of wedded union is of such importance to God that He even permitted women to leave their parents and to cleave to their husbands. But why is it written in Genesis (Gen. 2:24) that Adam said, "Therefore shall a man leave his father and his mother," while here Christ says that it was God Who said, "For this cause shall a man leave father and mother." We say, therefore, that what Adam spoke, he spoke from God, so that the speech of Adam is of God.

Commentary on Matthew ↗

Augustine of Hippo

Whereas Scripture witnesses that these words were said by the first man, and the Lord here declares that God spake them, hence we should understand that by reason of the ecstasy which had passed upon Adam, he was enabled to speak this as a prophecy.

Catena Aurea by Aquinas ↗

Jerome

And he said: Because of this, a man will leave his father and mother and be united to his wife, and the two will become one flesh. So they are no longer two, but one flesh. Likewise, he said, a man must be united to his wife, not wives. And the two will become one flesh. The reward of marriage is for two to become one flesh. Chastity joined to the spirit makes one spirit. Therefore, what God has joined together, let no man separate. …

Commentary on Matthew ↗

Thomas Aquinas

For this cause a man shall leave father and mother. Here he presents the affection which he implanted. And he said. Who said? He who made them. But this does not seem right, because it seems that Adam said it. Augustine says that the Lord sent a deep sleep upon Adam and took one of his ribs. This sleep was an ecstasy; hence there he revealed many good things; hence the Lord also revealed to him what is said here; hence above at 10:20 it was said: for it is not you who speak, but the spirit of your Father who speaks in you. …

Commentary on Matthew ↗