Clement of Alexandria

Again, it is said, "He tethers his colt to the vine." This means he united the simple, new people to the Word, whom the vine signifies. For the product of the vine is wine; of the Word, blood. Both are saving potions: wine, for the health of the body; the other, blood, for the salvation of the soul.

The Instructor Book 1 ↗

Ambrose of Milan

"He will wash his robe in wine." The good robe is the flesh of Christ, which has covered the sins of all people, taken up the offenses of all, concealed the misdeeds of all—the good robe which has clothed all people with the garment of rejoicing. He washed this robe in wine at his baptism in the Jordan, when the Holy Spirit came down like a dove and remained upon him. By this, it is indicated that the fullness of the Holy Spirit will be indivisible in him and will not depart. …

On the Blessings of the Patriarchs ↗

Jerome

He ties his young donkey to the vine, and the colt of the donkey to the choice vine. In Hebrew it says, He ties his young donkey to the vine, and in Sorec, his donkey's colt to the choice vine: which colt of the donkey, that is, the Gentile people whom Jesus has taken over, that is, the Apostles' vineyard, who are from the Jews, he has joined together. And in Sorec, that is, the chosen vine, he has tied the donkey, over whom he has taken control, the Church gathered from the nations. …

Hebrew Questions on Genesis ↗

Hippolytus of Rome

By the "foal" he means the calling of the Gentiles; by the other, that of the circumcision: "one ass," moreover, that is to signify that the two colts are of one faith; in other words, the two callings. And one colt is bound to the "vine," and the other to the "vine tendril," which means that the Church of the Gentiles is bound to the Lord, but he who is of the circumcision to the oldness of the law. …

Hippolytus Exegetical Fragments ↗