Ambrose of Milan

And so, I recognize more clearly what I read: For the wheel runs within the wheel and is not hindered (Ezek. 1:16-17). For he passes his life without any offense in any passion, and even within these things the wheel runs. The Law runs within grace, and obedience to the Law is within the course of divine mercy: for the more it turns, the more it is proven.

On Jacob and the Blessed Life 2.11.49 ↗

Jerome

And as I looked at the animals, a wheel appeared on the earth beside the animals, having four faces. And the appearance of the wheels and their work was like the vision of the sea, and the four of them had the same likeness, and their appearance and work was as a wheel within a wheel. They went in the four directions, and they did not turn as they walked. The wheels also had a height and a terrifying appearance, and the whole body was full of eyes all around the four of them. …

Commentary on Ezekiel ↗

Gregory the Dialogist

But what does the wheel signify except sacred Scripture, which turns from every side toward the minds of its hearers, and is held back from the way of its preaching by no corner of error? It turns from every side because amid adversity and prosperity it proceeds rightly and humbly. …

Homilies on Ezekiel, Book 1, Homily 6 ↗