John Chrysostom

And then the greatness of the punishment: "And it shall come to pass, that every soul which will not hear that Prophet, shall be destroyed from among the people. Yea, and all the prophets, from Samuel and those that follow, after, as many as have spoken have likewise foretold of these days." He has done well to set the distinction here. For whenever he says anything great, he appeals to them of old. …

Homily on Acts 9 ↗

Theophylact of Ohrid

"Shall be destroyed from among the people." Being immortal, the human soul is not completely destroyed, but falls from whatever good state it had previously been placed in. So too Judas was destroyed, that is, excluded from the ranks of the apostles. Therefore, since the soul is immortal, by its destruction we understand the deprivation of those blessings which it would have tasted if it had lived in a manner pleasing to God.

Commentary on Acts ↗

Bede

But it shall be, every soul who does not listen to that prophet shall be cut off from the people. Truly, it should be noted that blessed Peter here did not care to hold onto the words of the Mosaic sentence, but the sense. For it is written in Deuteronomy, with Moses speaking to the sons of Israel: The Lord your God will raise up for you a prophet from among your nation and from your brethren like me, you shall listen to him, as you asked of the Lord your God at Horeb (Deut. XVIII). …

Retractions on Acts ↗